NCAA Football Best Games Week 5

There are several strong matchups on the Week 5 FBS college football schedule, including the Maryland Terrapins taking on the Indiana Hoosiers.

Here are the betting odds to dissect before Week 5 in college football.

Keep reading for our betting primers for this season, and discover all of our predictions here, too!

Week 5’s Best College Football Games

Maryland (3-1) at Indiana (4-0)

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  • Game Time: 12:00 PM ET | Saturday, September 28, 2024
  • Venue: Memorial Stadium (Bloomington, IN)
  • Location: Bloomington, Indiana
Odds to Cover

Indiana -7.5 vs. Maryland

Bet $20, Payout $38.69

No. 2 Georgia (3-0) at No. 4 Alabama (3-0)

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  • Game Time: 7:30 PM ET | Saturday, September 28, 2024
  • Venue: Bryant-Denny Stadium
  • Location: Tuscaloosa, Alabama
Spread

Georgia -1 vs. Alabama

Bet $20, Payout $38.18

No. 3 Ohio State (3-0) at Michigan State (3-1)

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  • Game Time: 7:30 PM ET | Saturday, September 28, 2024
  • Venue: Spartan Stadium
  • Location: East Lansing, Michigan
Odds to Cover

Ohio State -23.5 vs. Michigan State

Bet $20, Payout $38.02

Virginia Tech (2-3) at No. 7 Miami (FL) (5-0)

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  • Game Time: 7:30 PM ET | Friday, September 27, 2024
  • Venue: Hard Rock Stadium
  • Location: Miami Gardens, Florida
Spread

Miami (FL) -17.5 vs. Virginia Tech

Bet $20, Payout $38.02

Washington State (4-0) at No. 25 Boise State (2-1)

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  • Game Time: 10:00 PM ET | Saturday, September 28, 2024
  • Venue: Albertsons Stadium
  • Location: Boise, Idaho
To Cover the Spread

Boise State -6.5 vs. Washington State

Bet $20, Payout $37.86

No. 15 Louisville (3-0) at No. 16 Notre Dame (3-1)

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  • Game Time: 3:30 PM ET | Saturday, September 28, 2024
  • Venue: Notre Dame Stadium
  • Location: South Bend, Indiana
Spread

Notre Dame -6.5 vs. Louisville

Bet $20, Payout $37.86

No. 19 Illinois (4-0) at No. 9 Penn State (3-0)

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  • Game Time: 7:30 PM ET | Saturday, September 28, 2024
  • Venue: Beaver Stadium
  • Location: University Park, Pennsylvania
Spread

Penn State -17.5 vs. Illinois

Bet $20, Payout $37.39

Washington (3-2) at Rutgers (4-0)

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  • Game Time: 8:00 PM ET | Friday, September 27, 2024
  • Venue: SHI Stadium
  • Location: Piscataway, New Jersey
Spread

Washington -1 vs. Rutgers

Bet $20, Payout $38.69

North Carolina (3-1) at Duke (4-0)

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  • Game Time: 4:00 PM ET | Saturday, September 28, 2024
  • Venue: Brooks Field at Wallace Wade Stadium
  • Location: Wilmington, North Carolina
To Cover the Spread

Duke -1 vs. North Carolina

Bet $20, Payout $38.18

Cincinnati (3-1) at Texas Tech (3-1)

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  • Game Time: 8:00 PM ET | Saturday, September 28, 2024
  • Venue: Jones AT&T Stadium
  • Location: Lubbock, Texas
Betting Odds

Texas Tech -3.5 vs. Cincinnati

Bet $20, Payout $38.87