USC vs. Michigan Spread, Line, Odds and Betting Preview | Sept. 21

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USC vs. Michigan Spread, Line & Odds for Sept. 21

Data Skrive:

One of the best wideouts in college football will be on display when Colston Loveland and the Michigan Wolverines (2-1) take on the USC Trojans (2-0) on Saturday, September 21, 2024.

The Trojans are favored, but by less than a touchdown (-4.5), versus the Wolverines. The over/under for this matchup is 44 points.

Keep reading to check out our betting primer for this season, and discover all of our betting picks here, too!

Odds to Cover

USC -4.5 vs. Michigan

Bet $20, Payout $38.18

USC vs. Michigan Betting Odds

  • Spread favorite: Trojans (-4.5)
  • Moneyline: Trojans (-190), Wolverines (+156)
  • Total: 44 points
  • TV Channel: CBS
  • Live Stream: Fubo (Watch for free)

USC vs. Michigan Betting Stats and Info

In two opportunities, the Trojans have won just twice against the spread. When favored by 4.5 points or more, the Trojans have covered the spread in all one game. USC won the only game it played when favored on the moneyline this season. Michigan, through three games with a set spread so far this season, has gone 0-3-0 against the spread. Against the spread, the Wolverines are winless in one game when underdogs by 4.5 points or more. This is the second time this year Michigan is an underdog on the moneyline. The Wolverines lost the first one.

USC vs. Michigan Key Players

USC Trojans

  • Last year Caleb Williams put up 3,633 passing yards (279.5 per game) while going 266-for-389 (68.4%) and throwing for 30 touchdowns with five interceptions.
  • A season ago MarShawn Lloyd picked up 820 rushing yards (63.1 per game) and scored nine touchdowns. He tacked on 13 catches for 232 yards .
  • Last year Austin Jones rushed for 477 yards on 85 carries (36.7 yards per game), with seven rushing touchdowns.
  • Last season Tahj Washington was targeted 77 times and notched 59 catches for 1,062 yards with eight touchdowns.
  • Brenden Rice chipped in with 45 grabs for 791 yards and 12 touchdowns.
  • Duce Robinson collected 351 receiving yards on 16 catches with two TDs.
  • Jamil Muhammad boasted an impressive stat line of 6.5 sacks, 8.0 TFL and 43 tackles last year.
  • Mason Cobb racked up 82 tackles and 5.0 TFL over the course of his last campaign.
  • Last season, Chris Roland-Wallace reeled in two interceptions and added 35 tackles, 3.0 TFL, and two passes defended.

Michigan Wolverines

  • Last season J.J. McCarthy racked up 2,991 passing yards (199.4 per game) while going 240-for-332 (72.3%) and throwing for 22 touchdowns with four interceptions. He added 202 rushing yards on 64 carries and three TDs.
  • Blake Corum racked up 1,245 rushing yards (83.0 per game) and scored 27 touchdowns.
  • Last year Donovan Edwards rushed for 497 yards on 119 carries (33.1 yards per game), with five rushing touchdowns. He also caught 30 passes for 249.
  • Last year Roman Wilson hauled in 48 passes for 789 yards (52.6 per game) and 12 touchdowns.
  • Loveland also tacked on 649 yards on 45 grabs and four touchdowns. He was targeted 65 times, and averaged 43.3 receiving yards last season.
  • Cornelius Johnson caught 47 passes on 70 targets for 604 yards and one TD.
  • Jaylen Harrell boasted an impressive stat line of 7.5 sacks, 7.0 TFL and 30 tackles.
  • Junior Colson’s 2023 campaign saw him total 95 tackles and 2.0 TFL.
  • Mike Sainristil picked off five passes while adding 46 tackles, 3.0 TFL, two sacks, and six passes defended a season ago.