Data Skrive:
The FBS college football slate in Week 6, which includes the Iowa Hawkeyes taking on the Ohio State Buckeyes, is not one to miss.
To gain an edge ahead of Week 6 in college football, check out our betting preview below.
Read on for our previews for this season, and discover all of our expert picks here, too!
Week 6’s Best College Football Games
Iowa (3-1) at No. 3 Ohio State (4-0)
- Game Time: 3:30 PM ET | Saturday, October 5, 2024
- Venue: Ohio Stadium
- Location: Columbus, Ohio
Betting Odds
Bet $20, Payout $38.35
Ohio State -17.5 vs. Iowa
Michigan State (3-3) at No. 6 Oregon (5-0)
- Game Time: 9:00 PM ET | Friday, October 4, 2024
- Venue: Autzen Stadium
- Location: Eugene, Oregon
Odds to Cover
Bet $20, Payout $38.35
Oregon -23.5 vs. Michigan State
No. 1 Alabama (4-0) at Vanderbilt (2-2)
- Game Time: 4:15 PM ET | Saturday, October 5, 2024
- Venue: FirstBank Stadium
- Location: Nashville, Tennessee
Odds to Cover
Bet $20, Payout $37.86
Alabama -22.5 vs. Vanderbilt
No. 12 Ole Miss (4-1) at South Carolina (3-1)
- Game Time: 3:30 PM ET | Saturday, October 5, 2024
- Venue: Williams-Brice Stadium
- Location: Columbia, South Carolina
Betting Odds
Bet $20, Payout $38.35
Ole Miss -10 vs. South Carolina
Baylor (2-3) at No. 16 Iowa State (4-0)
- Game Time: 7:30 PM ET | Saturday, October 5, 2024
- Venue: Jack Trice Stadium
- Location: Ames, Iowa
Betting Odds
Bet $20, Payout $38.02
Iowa State -11.5 vs. Baylor
No. 4 Tennessee (4-0) at Arkansas (3-2)
- Game Time: 7:30 PM ET | Saturday, October 5, 2024
- Venue: Donald W. Reynolds Razorback Stadium
- Location: Fayetteville, Arkansas
Spread
Bet $20, Payout $38.18
Tennessee -14 vs. Arkansas
SMU (4-1) at No. 22 Louisville (3-1)
- Game Time: 12:00 PM ET | Saturday, October 5, 2024
- Venue: L&N Federal Credit Union Stadium
- Location: Louisville, Kentucky
Odds to Cover
Bet $20, Payout $37.09
Louisville -6.5 vs. SMU
Rutgers (4-0) at Nebraska (4-1)
- Game Time: 4:00 PM ET | Saturday, October 5, 2024
- Venue: Memorial Stadium (Lincoln, NE)
- Location: Lincoln, Nebraska
Odds to Cover
Bet $20, Payout $37.39
Nebraska -6.5 vs. Rutgers
No. 23 Indiana (5-0) at Northwestern (2-2)
- Game Time: 3:30 PM ET | Saturday, October 5, 2024
- Venue: Lanny and Sharon Martin Athletics Facility
- Location: Evanston, Illinois
Odds to Cover
Bet $20, Payout $38.18
Indiana -13.5 vs. Northwestern
Boston College (4-1) at Virginia (3-1)
- Game Time: 12:00 PM ET | Saturday, October 5, 2024
- Venue: Scott Stadium
- Location: Charlottesville, Virginia
Betting Odds
Bet $20, Payout $37.86
Virginia -1.5 vs. Boston College