Iowa State vs. Houston Spread, Line, Odds and Betting Preview | Sept. 28

The Houston Cougars (1-3) play on Saturday at 7:00 p.m. ET at John O’Quinn Field at TDECU Stadium against the Iowa State Cyclones (3-0).

The Cougars are expected to lose by at least two TDs (currently +16.5) against the Cyclones (with an over/under of 42.5 points).

Below you can find our preview for this season, and discover all of our predictions here, too!

Betting Odds

Iowa State -16.5 vs. Houston

Bet $20, Payout $38.87

Iowa State vs. Houston Betting Odds

  • Spread favorite: Cyclones (-16.5)
  • Moneyline: Cyclones (-813), Cougars (+548)
  • Total: 42.5 points
  • TV Channel: FOX Sports Networks
  • Live Stream: Fubo (Watch for free)

Iowa State vs. Houston Betting Stats and Info

Against the spread, the Cyclones have won all two games. The Cyclones’ record against the spread, when favored by 16.5 points or more, is a perfect 1-0. Iowa State won the lone game it played as the moneyline favorite this season. Houston has a pair of wins against the spread so far this season (2-2-0). When underdogs by 16.5 points or more, the Cougars have covered the spread in all one game. This will be the third time this year Houston is an underdog on the moneyline, after losing the previous two such games.

Iowa State vs. Houston Key Players

Iowa State Cyclones

  • Rocco Becht has passed for 743 yards (54-for-79), with six touchdowns and two interceptions (247.7 yards per game).
  • Abu Sama III has run for a team-high 124 yards (41.3 YPG) and zero touchdowns.
  • Jaylon Jackson has run for 92 yards (30.7 per game).
  • Jaylin Noel has 15 catches (on 20 targets) and leads the team with 317 receiving yards (105.7 per game) while scoring two touchdowns.
  • Jayden Higgins has also contributed with 17 catches for 208 yards and three touchdowns. He has been targeted 19 times and averages 69.3 receiving yards per game.
  • Benjamin Brahmer has collected 96 yards on five receptions, averaging 32 yards per game.
  • J.R. Singleton has notched a team-leading two sacks, while adding two TFL and nine tackles.
  • Malik Verdon has totaled 22 tackles, two TFL, and one interception, and he’s tops on his team in tackles.
  • This season Darien Porter leads the team with two interceptions and has added three tackles and two passes defended.

Houston Cougars

  • This year Donovan Smith has recorded 610 passing yards (152.5 per game) while going 62-for-95 (65.3%) and throwing for two touchdowns with four interceptions. He has tacked on 43 rushing yards on 36 carries with two touchdowns.
  • Re’Shaun Sanford II has rushed for a team-leading 166 yards on 32 attempts (41.5 yards per game). He also averages 24 receiving yards per game, grabbing eight passes for 96 yards.
  • So far this year Stacy Sneed has run for 138 yards on 26 carries (34.5 yards per game), with one touchdown.
  • Joseph Manjack IV has racked up 10 catches for 146 yards, best on his team, and two touchdowns. He averages 36.5 receiving yards per game.
  • Stephon Johnson Jr.’s stat line this year reveals 11 catches for 132 yards and one touchdown. He averages 33 receiving yards per game.
  • Mekhi Mews has 105 receiving yards on 12 receptions (19 targets).
  • Keith Cooper Jr. has notched a team-leading two sacks, while adding four TFL and 14 tackles.
  • Michael Batton’s 28 tackles, three TFL, and two sacks make him the team’s leading tackler.
  • In terms of picks, Jeremiah Wilson leads the team with one interception this season and has added five tackles and one pass defended.