Cardinals vs. Guardians Betting Odds, Pitching Matchup – September 21, 2024

The Cleveland Guardians (90-65) roll into Saturday’s matchup with the St. Louis Cardinals (77-77) looking to extend a three-game winning streak. The contest starts at 7:15 p.m. ET on BSGL with the Cardinals listed as -117 favorites on the moneyline to stop the Guardians’ streak. St. Louis’ Miles Mikolas and Cleveland’s Matthew Boyd have been named the starters for this contest.

Here is our betting primer for this contest, and find all of our expert MLB picks, too!

Cardinals vs. Guardians Betting Lines

• Favorite: Cardinals (-117)
• Underdog: Guardians (-102)
• Over/under: 8

Cardinals vs. Guardians Betting Insights

• The Cardinals have won in 37, or 50.7%, of the 73 contests they have been named as odds-on favorites in this year.
• St. Louis has a record of 30-30 when favored by -117 or more this year.
• The Cardinals have an implied victory probability of 53.9% according to the moneyline set by sportsbooks for this matchup.
• The Guardians are 27-30 in games they were the underdog on the moneyline (winning 47.4% of those games).
• Cleveland is 20-29 (winning 40.8% of its games) when it has played as a moneyline underdog of -102 or longer.
• Based on this game’s moneyline, the Guardians’ implied win probability is 50.5%.

Cardinals vs. Guardians Hitting Leaders

• Brendan Donovan leads St. Louis with a batting average of .275. He’s also hit 13 home runs with 68 RBI.
• Of all hitters in MLB, Donovan’s home run total ranks him 146th and his RBI tally ranks him 71st.
• Alec Burleson is batting .269 this season with a team-high 21 home runs and 73 RBI.
• Jose Ramirez has a team-best 36 home runs and 109 runs batted in.
• Among all hitters in the big leagues, Ramirez is eighth in home runs and fourth in RBI.
• Josh Naylor is hitting .243 with 26 doubles, 31 home runs and 56 walks.

Cardinals vs. Guardians Pitching Rankings

• The Cardinals have an 8.2 K/9 this season as a pitching staff, which ranks 26th in baseball.
• The Cardinals have pitched to a 4.07 ERA this season, which ranks 16th in baseball.
• Cardinals pitchers have a 1.263 WHIP this season, 17th in the majors.
• The Guardians pitching staff is eighth in the majors with a collective 8.9 strikeouts per nine innings.
• Cleveland has a 3.66 team ERA that ranks fourth across all MLB pitching staffs.
• Guardians pitchers combine for the No. 3 WHIP in the majors (1.200).