Bet on Bills vs. Cardinals in New Jersey: Betting Odds, Line and Spread

Data Skrive:

The Buffalo Bills (0-0) and the Arizona Cardinals (0-0) meet on Sunday at Highmark Stadium.

The Cardinals are 6.5-point underdogs against the Bills (the game has an over/under of 46.5 points).

Take a look at our betting primer for this matchup, and uncover all of our NFL picks, too!

Odds to Win

Bills to win vs Cardinals -301

Bet $20, Payout $26.64

Bills vs. Cardinals Betting Information

The Cardinals beat the spread eight times in 17 games last season.
The Cardinals’ ATS record as underdogs of 6.5 points or greater was 4-5 last season.
The Cardinals had 10 of their 17 games hit the over last season.

The Bills ranked ninth in total defense last season (307.2 yards allowed per game), but they played really well on the offensive side of the ball, ranking fourth-best in the NFL with 374.5 total yards per game.
The Bills ranked sixth in points scored last season (26.5 points per game), but they thrived on defense, ranking fourth-best in the NFL with 18.3 points allowed per game.
Offensively, the Bills ranked eighth in the NFL with 244.4 passing yards per game last season. Meanwhile, they ranked seventh in passing yards allowed per contest (196.6).
The Bills ranked seventh in run offense (130.1 rushing yards per game) and 15th in run defense (110.6 rushing yards allowed per game) last season.
On offense, the Bills were a top-five unit in terms of third-down efficiency last season, ranking best in the NFL by putting up a 49.8% third-down percentage. They ranked 18th on defense (38.6% third-down conversion rate allowed).

On offense, the Cardinals ranked 19th in the NFL with 324.1 yards per game last season. Meanwhile, they ranked 25th in total defense (355.7 yards allowed per contest).
The Cardinals had the 24th-ranked scoring offense last year (19.4 points per game), and they were less effective on the other side of the ball, ranking second-worst with 26.8 points allowed per game.
The Cardinals ranked 26th in pass offense (184.9 passing yards per game) and 13th in pass defense (212.5 passing yards allowed per game) last year.
The Cardinals owned the fourth-best offense last season in terms of rushing yards (139.1 rushing yards per game), but they ranked worst on defense (143.2 rushing yards allowed per game).
In addition to a 47.3% third-down percentage allowed on defense last season, which ranked worst in the NFL, the Cardinals put up the 14th-ranked third-down conversion rate (39.1%) on offense.

Josh Allen: 4,306 PASS YDS / 253.3 YPG / 66.5% / 29 TD / 18 INT / 111 CAR / 524 RUSH YDS / 15 TD
James Cook: 237 CAR / 1,122 YDS / 66.0 YPG / 2 TD / 44 REC / 445 YDS / 26.2 YPG / 4 TD
Dalton Kincaid: 73 REC / 673 YDS / 42.1 YPG / 2 TD
Curtis Samuel: 62 REC / 613 YDS / 38.3 YPG / 4 TD

Kyler Murray: 1,799 PASS YDS / 224.9 YPG / 65.7% / 10 TD / 5 INT / 44 CAR / 244 RUSH YDS / 3 TD
James Conner: 208 CAR / 1,040 YDS / 80.0 YPG / 7 TD / 27 REC / 165 YDS / 12.7 YPG / 2 TD
Emari Demercado: 58 CAR / 284 YDS / 25.8 YPG / 2 TD / 21 REC / 119 YDS / 10.8 YPG / 0 TD
Trey McBride: 81 REC / 825 YDS / 48.5 YPG / 3 TD
Michael Wilson: 38 REC / 565 YDS / 43.5 YPG / 3 TD